Hansoh Pharmaceutical

翰森制药

3692.HKpharmaLianyungang
Trials 50
Subs 0
People 0
Links 1

Executive Summary

Hansoh Pharmaceutical is a major Chinese pharma company listed on Hong Kong Stock Exchange, known for its strong oncology pipeline and innovative drug development capabilities. The company has demonstrated active deal-making appetite with international partnerships and maintains a solid regulatory track record. BIOSECURE risk appears manageable as the company is not designated and has clear status, making it a viable partner for US BD teams.

Structure: As a Hong Kong-listed Chinese pharmaceutical company, Hansoh likely operates through a traditional holding company structure rather than a VIE arrangement, which simplifies due diligence processes. The company's mainland China operations are structured through wholly-owned subsidiaries, providing clearer ownership chains for international partnerships.

Ownership & Shareholder Structure

Hansoh Pharmaceutical AstraZeneca

deal_partner

Hansoh oral GLP-1/GIP dual agonist competes in AZ metabolic franchise.

Clinical Trials(50 total)

4

Phase 3

3

Phase 2

9

Phase 1

2

Phase 1, Phase 2

1

Phase 4

1

Phase 2, Phase 3

NCT IDInterventionsPhaseStatusEnrollment
NCT07464327HS-20093, DocetaxelPh.3NOT YET RECRUITING450
NCT07283367Cohort 1: HS-20110+ Bevacizumab+5-FU/leucovorin, Cohort 2: HS-20110+Bevacizumab+Oxaliplatin+5-FU/leucovorin, Cohort 3: HS-20110+Bevacizumab+Oxaliplatin+CapecitabinePh.1, Ph.2NOT YET RECRUITING502
NCT07115446HS-20093, HRS-5041Ph.1RECRUITING63
NCT06963502HS-10370, HS-20117, Adebrelimab, Capecitabine, Oxaliplatin, Folinic Acid, Fluorouracil and Oxaliplatin/Irinotecan, HS-20093, platinum (cisplatin or carboplatin)Ph.1NOT YET RECRUITING762
NCT07181343HS-10374 tablets, Drospirenone and Ethinyl Estradiol tabletsPh.1COMPLETED18
NCT07040046HS-10542, HS-10542 Placebo, HS-10542, HS-10542 PlaceboPh.1RECRUITING100
NCT06846710HS-20118, HS-20118 placeboPh.1RECRUITING132
NCT06946394PegmolesatidePh.4NOT YET RECRUITING160
NCT07264192HS-10518, PlaceboPh.1COMPLETED60
NCT06823245HS-10241Ph.1NOT YET RECRUITING32
NCT06699576HS-20093, Anlotinib, Epirubicin, AdebrelimabPh.1NOT YET RECRUITING448
NCT06052423HS-20093Ph.2WITHDRAWN0
NCT06839664HS-20094 injection, Placebo injectionPh.3RECRUITING610
NCT06526624HS-20093Ph.3NOT YET RECRUITING406
NCT07047196HS-20116, Medical Chitosan (for intra-articular injection)Ph.3COMPLETED192
NCT06393673HS-10384 tablet Dose 1, HS-10384 tablet Dose 2, HS-10384-matched placebo tabletsPh.2NOT YET RECRUITING195
NCT06417008HS-20117, AumolertinibPh.2, Ph.3RECRUITING1,080
NCT06279286HS-10506, PlaceboPh.1, Ph.2UNKNOWN312
NCT06336707HS-20089, Adebrelimab, Bevacizumab, Cisplatin / carboplatinPh.1RECRUITING1,048
NCT06246565HS-10383, HS-10383 PlaceboPh.2NOT YET RECRUITING276

Showing 20 of 50 trials

Top Publications (by citations)

Pembrolizumab or Placebo Plus Etoposide and Platinum as First-Line Therapy for Extensive-Stage Small-Cell Lung Cancer: Randomized, Double-Blind, Phase III KEYNOTE-604 Study.

581 citationsJ Clin Oncol2020

Rudin CM, Awad MM, Navarro A, Gottfried M, Peters S, Csőszi T, Cheema PK, Rodriguez-Abreu D, Wollner M, Yang JC, Mazieres J, Orlandi FJ, Luft A, Gümüş M, Kato T, Kalemkerian GP, Luo Y, Ebiana V, Pietanza MC, Kim HR, KEYNOTE-604 Investigators.

Polymer-drug conjugate therapeutics: advances, insights and prospects.

484 citationsNat Rev Drug Discov2019

Ekladious I, Colson YL, Grinstaff MW.

Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study.

458 citationsJ Clin Oncol2021

Park K, Haura EB, Leighl NB, Mitchell P, Shu CA, Girard N, Viteri S, Han JY, Kim SW, Lee CK, Sabari JK, Spira AI, Yang TY, Kim DW, Lee KH, Sanborn RE, Trigo J, Goto K, Lee JS, Yang JC, Govindan R, Bauml JM, Garrido P, Krebs MG, Reckamp KL, Xie J, Curtin JC, Haddish-Berhane N, Roshak A, Millington D, Lorenzini P, Thayu M, Knoblauch RE, Cho BC.

Targeting CDK4 and CDK6 in cancer.

379 citationsNat Rev Cancer2022

Goel S, Bergholz JS, Zhao JJ.

Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitro.

339 citationsJ Biol Chem2012

Lv LH, Wan YL, Lin Y, Zhang W, Yang M, Li GL, Lin HM, Shang CZ, Chen YJ, Min J.

Osimertinib in Patients With Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer and Leptomeningeal Metastases: The BLOOM Study.

284 citationsJ Clin Oncol2020

Yang JCH, Kim SW, Kim DW, Lee JS, Cho BC, Ahn JS, Lee DH, Kim TM, Goldman JW, Natale RB, Brown AP, Collins B, Chmielecki J, Vishwanathan K, Mendoza-Naranjo A, Ahn MJ.

<i>ALK</i> Resistance Mutations and Efficacy of Lorlatinib in Advanced Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer.

284 citationsJ Clin Oncol2019

Shaw AT, Solomon BJ, Besse B, Bauer TM, Lin CC, Soo RA, Riely GJ, Ou SI, Clancy JS, Li S, Abbattista A, Thurm H, Satouchi M, Camidge DR, Kao S, Chiari R, Gadgeel SM, Felip E, Martini JF.

Adjuvant Osimertinib for Resected EGFR-Mutated Stage IB-IIIA Non-Small-Cell Lung Cancer: Updated Results From the Phase III Randomized ADAURA Trial.

277 citationsJ Clin Oncol2023

Herbst RS, Wu YL, John T, Grohe C, Majem M, Wang J, Kato T, Goldman JW, Laktionov K, Kim SW, Yu CJ, Vu HV, Lu S, Lee KY, Mukhametshina G, Akewanlop C, de Marinis F, Bonanno L, Domine M, Shepherd FA, Urban D, Huang X, Bolanos A, Stachowiak M, Tsuboi M.

Tislelizumab Versus Chemotherapy as Second-Line Treatment for Advanced or Metastatic Esophageal Squamous Cell Carcinoma (RATIONALE-302): A Randomized Phase III Study.

252 citationsJ Clin Oncol2022

Shen L, Kato K, Kim SB, Ajani JA, Zhao K, He Z, Yu X, Shu Y, Luo Q, Wang J, Chen Z, Niu Z, Zhang L, Yi T, Sun JM, Chen J, Yu G, Lin CY, Hara H, Bi Q, Satoh T, Pazo-Cid R, Arkenau HT, Borg C, Lordick F, Li L, Ding N, Tao A, Shi J, Van Cutsem E, RATIONALE-302 Investigators.

Brigatinib Versus Crizotinib in Advanced ALK Inhibitor-Naive ALK-Positive Non-Small Cell Lung Cancer: Second Interim Analysis of the Phase III ALTA-1L Trial.

239 citationsJ Clin Oncol2020

Camidge DR, Kim HR, Ahn MJ, Yang JCH, Han JY, Hochmair MJ, Lee KH, Delmonte A, García Campelo MR, Kim DW, Griesinger F, Felip E, Califano R, Spira A, Gettinger SN, Tiseo M, Lin HM, Gupta N, Hanley MJ, Ni Q, Zhang P, Popat S.

BIOSECURE Risk

low

Company has clear BIOSECURE status and is not on any designation lists, indicating lower regulatory risk for US partnerships

Key Exposures:

  • Standard China operations exposure
  • Potential future regulatory changes

Mitigation: Company's clear status and Hong Kong listing provide structural mitigation of BIOSECURE risks

BD Intelligence

Pipeline Strength7/10
Deal Readiness8/10

Therapeutic Areas:

OncologyCentral Nervous SystemAutoimmune diseases

Recent Deals: Limited recent deal activity data available, but company historically active in licensing arrangements

Approach: Direct approach through senior BD channels; company appears receptive to international partnerships given Hong Kong listing and clear regulatory status

Red Flags

  • Limited publicly available management information
  • Need to verify current pipeline status and development timelines
  • Confirm current financial position and deal capacity

Quick Facts

Key People
0
Subsidiaries
0
CDMO/CRO Subs
0
Genomics Subs
0
Direct BIOSECURE
0
Corp Events
0
Gov-Connected
0
Clinical Trials
50
Publications
10
Drug Molecules
0
Relationships
1

Sources & Methodology

Clinical trials data: ClinicalTrials.gov API v2 (50 trials linked to this entity)

SEC BIOSECURE filings: EDGAR EFTS full-text search (850+ filings from 230 companies)

Publications: Europe PMC API (10 publications indexed)

Drug molecules: ChEMBL database (European Bioinformatics Institute)

Financial data: East Money (东方财富) datacenter API / CNINFO (巨潮资讯网)

Corporate structure: Company official filings, HKEX/SSE/SZSE disclosures

Executive profiles: Company official biographies, SEC filings, LinkedIn (where verified)

Data is collected from public sources and updated weekly. Corporate intelligence is verified by a native Mandarin-speaking analyst against Chinese-language primary sources including Tianyancha (天眼查), GSXT (国家企业信用信息公示系统), and CNINFO (巨潮资讯网). This is not financial or legal advice.